Hormone pellets are derived from plants, just like other forms of BHRT, meaning they are naturally-based and structurally identical to the hormones produced by the human body. Pellets are currently available for two types of hormone therapy – testosterone and estradiol. Each pellet is about the size of a grain of rice and is inserted into an incision made to the upper hip area during a simple, in-office procedure. Following insertion, the body slowly begins to metabolize the pellet, releasing a steady, natural dose of hormones—much like the body does under normal function—over the course of three to six months. The duration depends on how quickly the body metabolizes the pellet.